randomized clinical trial showed that immediate use of HAART led to a 96%
decrease in HIV transmission events within HIV serodiscordant heterosexual
couples. However, the generalizability of the effect of HAART, and the population-level impact on HIV transmission continues to generate substantial debate. We, therefore, conducted a review of the evidence regarding the preventive effect of HAART on HIV transmission within the context of the Bradford Hill criteria for causality.