Targeting asymptomatic malaria infections: active surveillance in control and elimination. The scale-up of interventions has reduced malaria burden across a number of countries. As transmission declines, it becomes focal, and programs need target the remaining parasite reservoirs. At very low transmission, elimination of malaria may involve finding and treating individual infections. Infections tend to cluster into foci related to environmental, climatic, and ecological suitability for vectors and transmission . At smaller scales, “hotspots", a household or groups of households, maintain higher transmission of malaria and a consistent reservoir of parasites throughout the year. Infections also cluster in demographic “hot" populations, or “hotpops". In low transmission or elimination settings, strategies for targeting these clusters, whether geographic or demographic, become important.
GlobalResearch at UCSF presents the broad scope of health research that is being conducted by UCSF researchers worldwide